To Your Good Health
Dear Dr. Roach: I am a snowbird who uses two different cardiologists for my health, and I am devoted to both of them. However, they have conflicting advice. I have coronary artery disease and had three stents placed in New York. I am an active 86-year-old woman who walks at least a mile daily and does light weights. My lab results are all normal. I take a daily baby aspirin and Plavix. Ive done well with them.
My Florida doctor wants me to discontinue the Plavix and take just the aspirin, but my New York doctor thinks I should keep the Plavix forever. I honestly dont know the right course of action. S.T.M.
Answer: Both aspirin and Plavix (clopidogrel) work by decreasing the activity of platelets, the specialized blood cells that start to form clots. They have been shown to reduce blockages of stents, which hold open blood vessels that have been unblocked via a catheter in the heart. There are several different types of stents, and some of them have medications embedded in them, which release slowly over many months. These drug-eluting stents require using both aspirin and clopidogrel for a longer period of time. There is some debate about how long to continue these medications, but I have not read any recommendations to continue them for more than 30 months. A study (the DAPT trial) used exact information about the person and the type of stent to make predictions about balancing risks, and the results of the study showed that in your case, using both aspirin and clopidogrel would reduce heart attack risk slightly, but at an increased risk of bleeding. Nonetheless, some cardiologists will continue both medications in some patients if there are no problems.