Dear Dr. Roach:
I have primary biliary cirrhosis, for which I take Actigall. My numbers are good now. I have had loose bowel movements since a colonoscopy several months ago, and sometimes I do not make it to the bathroom in time! My doctors have not given me any advice. — S.P.
Answer: Primary biliary cirrhosis is an autoimmune disease, meaning the body attacks its own cells. In this case, it’s the bile ducts in the liver. This causes progressive damage to the bile ducts and eventually leads to cirrhosis and liver failure. What triggers the autoimmune attack on the bile ducts is not known, but environmental factors are suspected.