Dear Dr. Roach: I was diagnosed with high LDL cholesterol 20 years ago. I have been taking higher statin doses and now take Crestor 20 mg. Due to muscle pain, my cardiologist prescribed Praluent injections of 75 mg every two weeks to lower my LDL to below 77. I am 74 and have two heart stents in my right coronary artery, but have never had a heart attack.
Praluent is a monoclonal antibody, and the literature states that it can lower your immunity. I also have low-grade (Gleason 3+3) prostate cancer that has been stable since diagnosed in 2012. Is there a risk that Praluent could cause my prostate cancer to advance? J.E.
Answer: Although taking a statin (such as the Crestor you were taking to reduce cholesterol) was once thought to increase cancer risk, multiple studies have since found no convincing evidence that this is the case.